We are currently looking for a
Higher Scientist
to join our
Analytical & Biological Sciences
Team within the
Science, Research & Innovation
group. This is a
full-time
opportunity, on a
fixed term contract/temporary promotion
basis. This post is grant funded and the contract is expected to last for
2 years.
The role will be lab based in South Mimms, Hertfordshire. Please be aware that this role can only be worked in the UK and not overseas. Who are we? The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. The Science, Research and Innovation (SR&I) group delivers public health impact through world-leading research and innovation to support clinical trials and availability of novel medicines. It comprises 6 sub-Groups: Innovation Accelerator, Clinical Investigations and Trials, Research and Development, Standards Lifecycle, Control Testing and Quality Assurance and Health & Safety. Analytical and Biological Sciences is a cross functional Research & Development team, which works closely with other teams within R&D but also teams within Standards Lifecycle and Control Testing. The team provides the ability to perform high-end analytical analysis and in-vivo testing of biological medicines. Analytically, we provide NMR spectroscopy, mass spectrometry, bioinformatics, and sequencing (NGS), statistics, formulation science. What’s the role? In this laboratory-based role, the postholder will contribute to cross-Departmental project teams involved in the development of biological reference standards by undertaking trial freeze drying studies, undertaking as part of the Formulation Science Team critical thermal analytical analyses of potential formulations, and delivering trial freeze-dried batches for biological characterisation and undertaking the necessary physicochemical QC testing. Key responsibilities: Contribute to core development work for the support of freeze-drying trials, undertaken in managed teams as part of the Future vaccines manufacturing Hub programme. Carry out analytical methods in support of designing cycles and assessing these products as required. Undertake the routine testing FD materials by non-invasive methods for moisture and oxygen headspace content. Collaborate with other internal scientists and communicate with colleagues, internal and external and Project Leaders. Who are we looking for? Our successful candidate will have: A BSc in a relevant subject plus ideally MSc degree or appropriate experience in life sciences or healthcare research. Previous experience and understanding of freeze drying and/or formulation of biological materials and technologies used to deliver this. Good working and theoretical knowledge/experience in biochemistry/analytical sciences e.g. HPLC, assay methodology. The ability to design experiments or investigate and troubleshoot a laboratory technique and to interrogate data to propose subsequent experimentation. Demonstrable understanding and previous experience of the application of Quality Management principles (e.g. ISO 9001, ISO 17025) in an analytical laboratory and awareness of the application of health and safety issues in a laboratory environment. If you would like to find out more about this fantastic opportunity, please read our
Job Description and Person Specification ! The selection process: We use the Civil Service Success Profiles to assess our candidates,
find out more here . Online application form , including questions based on the Behaviour, Experience and Technical Success Profiles.
Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application. Interview , which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of
‘Describe your previous experience of freeze drying or formulation development of biologics’. Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the answers provided - ensure you have read the questions thoroughly and allow sufficient time. You can view the criteria for this role in the job description. Applicants must ensure that anything submitted is
factually accurate and truthful . Plagiarism can include presenting the ideas and experience of others, or generated by artificial intelligence, as your own. If you require any disability related adjustments at any point during the process, please contact
careers@mhra.gov.uk
as soon as possible. Closing date: 26 January 2025 Shortlisting date: W/C 27 January 2025 Interview date: W/C 3 February 2025 Candidates will be contacted within a week of the sift and the interviews completed to inform them of the outcome. If you need assistance applying for this role or have any other questions, please contact
careers@mhra.gov.uk .
#J-18808-Ljbffr
Higher Scientist
to join our
Analytical & Biological Sciences
Team within the
Science, Research & Innovation
group. This is a
full-time
opportunity, on a
fixed term contract/temporary promotion
basis. This post is grant funded and the contract is expected to last for
2 years.
The role will be lab based in South Mimms, Hertfordshire. Please be aware that this role can only be worked in the UK and not overseas. Who are we? The Medicines and Healthcare products Regulatory Agency enhance and improve the health of millions of people every day through the effective regulation of medicines and medical devices, underpinned by science and research. The Science, Research and Innovation (SR&I) group delivers public health impact through world-leading research and innovation to support clinical trials and availability of novel medicines. It comprises 6 sub-Groups: Innovation Accelerator, Clinical Investigations and Trials, Research and Development, Standards Lifecycle, Control Testing and Quality Assurance and Health & Safety. Analytical and Biological Sciences is a cross functional Research & Development team, which works closely with other teams within R&D but also teams within Standards Lifecycle and Control Testing. The team provides the ability to perform high-end analytical analysis and in-vivo testing of biological medicines. Analytically, we provide NMR spectroscopy, mass spectrometry, bioinformatics, and sequencing (NGS), statistics, formulation science. What’s the role? In this laboratory-based role, the postholder will contribute to cross-Departmental project teams involved in the development of biological reference standards by undertaking trial freeze drying studies, undertaking as part of the Formulation Science Team critical thermal analytical analyses of potential formulations, and delivering trial freeze-dried batches for biological characterisation and undertaking the necessary physicochemical QC testing. Key responsibilities: Contribute to core development work for the support of freeze-drying trials, undertaken in managed teams as part of the Future vaccines manufacturing Hub programme. Carry out analytical methods in support of designing cycles and assessing these products as required. Undertake the routine testing FD materials by non-invasive methods for moisture and oxygen headspace content. Collaborate with other internal scientists and communicate with colleagues, internal and external and Project Leaders. Who are we looking for? Our successful candidate will have: A BSc in a relevant subject plus ideally MSc degree or appropriate experience in life sciences or healthcare research. Previous experience and understanding of freeze drying and/or formulation of biological materials and technologies used to deliver this. Good working and theoretical knowledge/experience in biochemistry/analytical sciences e.g. HPLC, assay methodology. The ability to design experiments or investigate and troubleshoot a laboratory technique and to interrogate data to propose subsequent experimentation. Demonstrable understanding and previous experience of the application of Quality Management principles (e.g. ISO 9001, ISO 17025) in an analytical laboratory and awareness of the application of health and safety issues in a laboratory environment. If you would like to find out more about this fantastic opportunity, please read our
Job Description and Person Specification ! The selection process: We use the Civil Service Success Profiles to assess our candidates,
find out more here . Online application form , including questions based on the Behaviour, Experience and Technical Success Profiles.
Please ensure all application questions are completed in full; your application may not be considered if any responses are left blank. Our applications are CV blind, and our Hiring Managers will not be able to access your CV when reviewing your application. Interview , which can include questions based on the Behaviour, Experience, Technical and Strengths Success Profiles. In the instance that we receive a high number of applications, we will hold an initial sift based on the lead criteria of
‘Describe your previous experience of freeze drying or formulation development of biologics’. Applicants are assessed on whether they meet any mandatory requirements as well as the necessary skills and experience for the role. Applications are scored based on the answers provided - ensure you have read the questions thoroughly and allow sufficient time. You can view the criteria for this role in the job description. Applicants must ensure that anything submitted is
factually accurate and truthful . Plagiarism can include presenting the ideas and experience of others, or generated by artificial intelligence, as your own. If you require any disability related adjustments at any point during the process, please contact
careers@mhra.gov.uk
as soon as possible. Closing date: 26 January 2025 Shortlisting date: W/C 27 January 2025 Interview date: W/C 3 February 2025 Candidates will be contacted within a week of the sift and the interviews completed to inform them of the outcome. If you need assistance applying for this role or have any other questions, please contact
careers@mhra.gov.uk .
#J-18808-Ljbffr
