Postdoctoral Fellow – P Znamenskiy Lab

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Full time
Location: London
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Category:
Salary for this Role: From £43,210 with benefits, subject to skills and experience Job Title: Postdoctoral Fellow – P Znamenskiy Lab Reports to: Petr Znamenskiy Closing Date: 02/Feb/2025 23.59 GMT Job Description: Details of the role: Salary: From £43,210 with benefits, subject to skills and experience Application closing date: 2nd February 2025 About us… The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. About the role… Using the primary visual cortex as a model, the Znamenskiy lab aims to understand how connections between different neuronal cell types are organized and how this organization enables the computations that they perform. If you hold a PhD in Neuroscience or a related field or in the final stages of PhD submission, this may be the perfect opportunity to join the lab. This role will offer you the chance to lead on your own projects, and also work in a team to contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and this may also include guiding PhD students in their research. What you will be doing… We have recently discovered that a large fraction of neurons in the primary visual cortex are selective for depth from motion parallax. This selectivity is a consequence of integration of optic flow and locomotion-related signals. This project will build on these findings to understand how depth-selective responses are transformed across the visual cortical hierarchy and how they arise in early visual circuits. To answer these questions, this project will use chronic two- and three-photon calcium imaging in mice navigating in three-dimensional virtual reality (VR) environments, pharmacological and optogenetic manipulation of neural activity, and high-density electrophysiological recordings in VR and in freely moving animals. About you… Essential PhD in Neuroscience or a related field or in the final stages of PhD submission Good knowledge and experience in in vivo calcium imaging or electrophysiology Experience in data analysis in Python or MATLAB Track record of writing papers as evidenced by publications or submitted manuscripts in referred journals Evidence of data presentation at scientific meetings Desirable Experience in stereotactic surgery in mice About Working at the Crick… Our values We are

bold . We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. We are

open . We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. We are

collegial . We show respect for one another, work cooperatively and support the wider community. The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment.

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