Job summary
The Synnovis Cancer Genetics laboratory at Guy's Hospital is part of the South East Genomics Laboratory Hub (SEGLH) and is the designated provider of adult solid tumour testing for the whole of the SEGLH geography. Large scale expansion and transformation of the service is underway to ensure equity of access to the NHSE National Genomic Test Directory for Cancer.
Main duties of the job
Your main duties will be to provide analytical support within the cancer team for haemato-oncology and solid tumour referrals.
A sound knowledge of laboratory genetics and experience of working within a cancer genetic team is essential; an in-depth knowledge of cancer genomics is required.
Excellent communication skills are necessary in order to work effectively with other staff both within Cancer Genetics at Guy's Hospital and the wider SEGLH team.
Job responsibilities
Service Delivery Participation in solid tumour NGS analysis workload including interpretation, reporting and administration. Accurately perform complex analysis of samples referred for Cancer analysis - this requires frequent and prolonged periods of concentration. Analytical techniques used will depend on individual competencies and training; duties are primarily NGS analysis of cancer samples. Check the analytical work of other team members in line with own individual competencies. This includes checking the analysis of staff at band 6 and below who are not HCPC registered. Responsibility for the final checking of a proportion of reports written by the team including; checking accuracy and interpretation of results and diagnostic and prognostic implications. Provision of highly specialised scientific advice and technical support to users of the diagnostic Cancer Genetics service and to other scientific and technical staff.
Quality and Management Participate in the preparation and implementation of Standard Operating Procedures (SOPs) and in the review of these documents. Ensure that work is carried out in line with Standard Operating Procedures and Departmental policy. Ensure the Departmental Health and Safety Policy are adhered to, and undertake the risk assessment of procedures as appropriate.
Education and Training Assist in the training of trainee scientists, biomedical scientists and medical staff. Encourage and support junior staff to develop their full potential for the benefit of the laboratory service and their careers. Promote the teaching and training of scientific, medical and technical staff and to collaborate in the effort to keep staff abreast of advances in human molecular genetics.
General duties Participate in working parties and liaison groups as necessary. Strictly adhere to local laboratory and Department of Health and Safety regulations and Codes of Practice. Demonstrate awareness of and compliance with Health and Safety regulations, Data Protection, and SOPs. Participate in laboratory and clinical audits. Ensure workplace and workbench areas are kept to laboratory standards. Undertake mandatory training as required by Synnovis. Maintain and promote the professional image of Synnovis. Participate in the PPR cycle, and be assessed against objectives relevant to the role of a clinical scientist. Participate in multidisciplinary team meetings when required.
Key Working Arrangements Work independently and autonomously rather than under direct supervision of more senior staff. Guidance is available from the Cancer Genetics operational management team as and when required.
Special Working Conditions Frequently undertake repetitive tasks involving the use of VDU resulting in prolonged periods of sitting in a restricted position. Monitor exposure to hazardous environmental and chemical substances. Undertake investigations of biological specimens which have adverse pathological risks associated with them. Frequent exposure to unpleasant working conditions due to the variety of specimens processed including tumour biopsies and bodily fluids. May be required to work shifts or provide out of hours cover as determined by service need and as directed in individual contracts of employment.
Person Specification
Qualifications Essential BSc in a relevant scientific discipline Registration as a Clinical Scientist with the Health Care Professions Council (HCPC) in Genetics/Cancer Genetics Completion of a recognised training programme in Cancer Genetics such as the NSHCS Scientific Training Programme (STP) Evidence of continuing professional development (CPD) Desirable Professional qualification such as FRCPath part 1 in Genetics or Molecular Pathology Higher degree in biological science Experience Essential Ability to troubleshoot practical issues arising within the cancer genetics laboratory Demonstrable specialist diagnostic cancer genetics experience gained by working in a team specialising in somatic cancer genetic analysis Experience of analysing cancer genetic samples using a range of techniques for molecular genetic and/or cytogenetic analysis Experience of writing clinical diagnostic reports for patients referred for cancer cytogenetic and/or molecular genetic testing. Desirable Experience of mutation analysis using appropriate PCR and Sanger sequencing methodologies Experience of fluorescence in situ hybridisation (FISH) analysis of formalin fixed paraffin embedded (FFPE) tissue sections Able to perform karyotype analysis by G-banding Experience of NGS data analysis and accompanying sequence variant interpretation Skills and Aptitudes/ Knowledge/ Ability Essential Ability to sit in a restricted position for prolonged periods e.g. at a computer Comprehensive theoretical knowledge of haematology/oncology and/or adult solid tumour genetics Ability to clearly communicate scientific and organizational information both in written and verbal form Experience of interpreting results for cancer genetic analysis Knowledge and application of Quality Control and compliance with ISO15189 standards Accuracy and attention to detail Good IT skills and knowledge of common computing packages Desirable Experience of clinical and technical validation of new tests Demonstrable supervisory work within a genetics laboratory An effective team member and leader Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions. UK Registration
Applicants must have current UK professional registration. #J-18808-Ljbffr
The Synnovis Cancer Genetics laboratory at Guy's Hospital is part of the South East Genomics Laboratory Hub (SEGLH) and is the designated provider of adult solid tumour testing for the whole of the SEGLH geography. Large scale expansion and transformation of the service is underway to ensure equity of access to the NHSE National Genomic Test Directory for Cancer.
Main duties of the job
Your main duties will be to provide analytical support within the cancer team for haemato-oncology and solid tumour referrals.
A sound knowledge of laboratory genetics and experience of working within a cancer genetic team is essential; an in-depth knowledge of cancer genomics is required.
Excellent communication skills are necessary in order to work effectively with other staff both within Cancer Genetics at Guy's Hospital and the wider SEGLH team.
Job responsibilities
Service Delivery Participation in solid tumour NGS analysis workload including interpretation, reporting and administration. Accurately perform complex analysis of samples referred for Cancer analysis - this requires frequent and prolonged periods of concentration. Analytical techniques used will depend on individual competencies and training; duties are primarily NGS analysis of cancer samples. Check the analytical work of other team members in line with own individual competencies. This includes checking the analysis of staff at band 6 and below who are not HCPC registered. Responsibility for the final checking of a proportion of reports written by the team including; checking accuracy and interpretation of results and diagnostic and prognostic implications. Provision of highly specialised scientific advice and technical support to users of the diagnostic Cancer Genetics service and to other scientific and technical staff.
Quality and Management Participate in the preparation and implementation of Standard Operating Procedures (SOPs) and in the review of these documents. Ensure that work is carried out in line with Standard Operating Procedures and Departmental policy. Ensure the Departmental Health and Safety Policy are adhered to, and undertake the risk assessment of procedures as appropriate.
Education and Training Assist in the training of trainee scientists, biomedical scientists and medical staff. Encourage and support junior staff to develop their full potential for the benefit of the laboratory service and their careers. Promote the teaching and training of scientific, medical and technical staff and to collaborate in the effort to keep staff abreast of advances in human molecular genetics.
General duties Participate in working parties and liaison groups as necessary. Strictly adhere to local laboratory and Department of Health and Safety regulations and Codes of Practice. Demonstrate awareness of and compliance with Health and Safety regulations, Data Protection, and SOPs. Participate in laboratory and clinical audits. Ensure workplace and workbench areas are kept to laboratory standards. Undertake mandatory training as required by Synnovis. Maintain and promote the professional image of Synnovis. Participate in the PPR cycle, and be assessed against objectives relevant to the role of a clinical scientist. Participate in multidisciplinary team meetings when required.
Key Working Arrangements Work independently and autonomously rather than under direct supervision of more senior staff. Guidance is available from the Cancer Genetics operational management team as and when required.
Special Working Conditions Frequently undertake repetitive tasks involving the use of VDU resulting in prolonged periods of sitting in a restricted position. Monitor exposure to hazardous environmental and chemical substances. Undertake investigations of biological specimens which have adverse pathological risks associated with them. Frequent exposure to unpleasant working conditions due to the variety of specimens processed including tumour biopsies and bodily fluids. May be required to work shifts or provide out of hours cover as determined by service need and as directed in individual contracts of employment.
Person Specification
Qualifications Essential BSc in a relevant scientific discipline Registration as a Clinical Scientist with the Health Care Professions Council (HCPC) in Genetics/Cancer Genetics Completion of a recognised training programme in Cancer Genetics such as the NSHCS Scientific Training Programme (STP) Evidence of continuing professional development (CPD) Desirable Professional qualification such as FRCPath part 1 in Genetics or Molecular Pathology Higher degree in biological science Experience Essential Ability to troubleshoot practical issues arising within the cancer genetics laboratory Demonstrable specialist diagnostic cancer genetics experience gained by working in a team specialising in somatic cancer genetic analysis Experience of analysing cancer genetic samples using a range of techniques for molecular genetic and/or cytogenetic analysis Experience of writing clinical diagnostic reports for patients referred for cancer cytogenetic and/or molecular genetic testing. Desirable Experience of mutation analysis using appropriate PCR and Sanger sequencing methodologies Experience of fluorescence in situ hybridisation (FISH) analysis of formalin fixed paraffin embedded (FFPE) tissue sections Able to perform karyotype analysis by G-banding Experience of NGS data analysis and accompanying sequence variant interpretation Skills and Aptitudes/ Knowledge/ Ability Essential Ability to sit in a restricted position for prolonged periods e.g. at a computer Comprehensive theoretical knowledge of haematology/oncology and/or adult solid tumour genetics Ability to clearly communicate scientific and organizational information both in written and verbal form Experience of interpreting results for cancer genetic analysis Knowledge and application of Quality Control and compliance with ISO15189 standards Accuracy and attention to detail Good IT skills and knowledge of common computing packages Desirable Experience of clinical and technical validation of new tests Demonstrable supervisory work within a genetics laboratory An effective team member and leader Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions. UK Registration
Applicants must have current UK professional registration. #J-18808-Ljbffr
