Lead engineer – Bioprocess Integration (Purification)
Apply locations UK - Slough Time type Full time Posted on Posted 16 Days Ago Job requisition id R60815 Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of. Role Purpose: Design, plan and execute studies in support of downstream integration and/or technology development projects with well-defined scope and timelines. Analyse study data to drive conclusions. Delivery: Develop innovative and robust intensification strategies for protein purification. Perform data trending and manufacturing cost analysis to benchmark process intensification strategies. Define the requirements for integrated protein purification in a manufacturing setting and create the development plan in collaboration with relevant stakeholders. Develop procedures to ensure equipment and unit operations are compatible with integration and automation. Define the strategy for the monitoring and control of integrated protein purification. Setup integrated purification process at lab-scale in collaboration with automation and digitalization specialists. Independently design studies, collate, evaluate/analyse and interpret complex data sets to achieve project targets. Write and execute detailed study plans with associated timelines. Author technical reports and publications with scientifically supported conclusions and recommendations. Work practices: Maintain accurate and timely records to appropriate quality standards for self and team, prepares high quality technical analyses and reports for internal or external use. Support team resource planning, project management activities and prioritisation decisions. Adhere to good laboratory practices and support housekeeping and maintenance activity. Maintain documentation describing configurations and setup of integrated process, process flow sheets and cost models. Key skills: Knowledge of downstream unit operations (separation basics, mass balance). Knowledge of Bioprocess equipment, advance automation and controls at lab scale. Demonstrated expertise in configuring lab scale equipment for integrated downstream processing. Hands-on experience in set up, execution and troubleshooting of downstream process intensification experiments using AKTA or appropriate filtration (Depth, UF/DF) set up. Compile data, perform data analysis and conclude observations (e.g data trending, chromatogram traces, MVDA etc.). Digital fluency in using tools required for data extraction, compilation, analysis and presentation. Other desired skills: Maintain accurate and timely records to appropriate quality standards for self and team, prepares high quality technical analyses and reports for internal or external use. Support team resource planning, project management activities and prioritisation decisions. Adhere to good laboratory practices and support housekeeping and maintenance activity. Maintain documentation describing configurations and setup of integrated process, process flow sheets and cost models. Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically. People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.
#J-18808-Ljbffr
Apply locations UK - Slough Time type Full time Posted on Posted 16 Days Ago Job requisition id R60815 Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of. Role Purpose: Design, plan and execute studies in support of downstream integration and/or technology development projects with well-defined scope and timelines. Analyse study data to drive conclusions. Delivery: Develop innovative and robust intensification strategies for protein purification. Perform data trending and manufacturing cost analysis to benchmark process intensification strategies. Define the requirements for integrated protein purification in a manufacturing setting and create the development plan in collaboration with relevant stakeholders. Develop procedures to ensure equipment and unit operations are compatible with integration and automation. Define the strategy for the monitoring and control of integrated protein purification. Setup integrated purification process at lab-scale in collaboration with automation and digitalization specialists. Independently design studies, collate, evaluate/analyse and interpret complex data sets to achieve project targets. Write and execute detailed study plans with associated timelines. Author technical reports and publications with scientifically supported conclusions and recommendations. Work practices: Maintain accurate and timely records to appropriate quality standards for self and team, prepares high quality technical analyses and reports for internal or external use. Support team resource planning, project management activities and prioritisation decisions. Adhere to good laboratory practices and support housekeeping and maintenance activity. Maintain documentation describing configurations and setup of integrated process, process flow sheets and cost models. Key skills: Knowledge of downstream unit operations (separation basics, mass balance). Knowledge of Bioprocess equipment, advance automation and controls at lab scale. Demonstrated expertise in configuring lab scale equipment for integrated downstream processing. Hands-on experience in set up, execution and troubleshooting of downstream process intensification experiments using AKTA or appropriate filtration (Depth, UF/DF) set up. Compile data, perform data analysis and conclude observations (e.g data trending, chromatogram traces, MVDA etc.). Digital fluency in using tools required for data extraction, compilation, analysis and presentation. Other desired skills: Maintain accurate and timely records to appropriate quality standards for self and team, prepares high quality technical analyses and reports for internal or external use. Support team resource planning, project management activities and prioritisation decisions. Adhere to good laboratory practices and support housekeeping and maintenance activity. Maintain documentation describing configurations and setup of integrated process, process flow sheets and cost models. Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically. People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.
#J-18808-Ljbffr
