Job Details: Senior Research Scientist II – Oncology Research, Functional Pharmacology
Vacancy Name:
Senior Research Scientist II – Oncology Research, Functional Pharmacology Vacancy No:
VN454 Employment Type:
Full Time Location of Role:
Abingdon, UK About the Company:
Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases, and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. Key Responsibilities: Lead projects and collaborate with colleagues to build pharmacology data on new drug formats (e.g., TCRm, multi-specifics) and effectors (including immune checkpoint- / cytokine-enhanced drugs). Establish in vitro assays for immunophenotyping drug MOA and response/resistance relationships. Establish drug libraries and screening workflows for investigating drug combinations and their effects on target/disease biology. Identify and test novel strategies to block/reprogramme immune or stromal cell subsets that generate suppressive TMEs. Generate patient stratified in vitro models of disease that accurately model drug target biology. Other Responsibilities: Collaborate with colleagues to build a deep knowledge around drug targets and cancer indications of strategic interest to Immunocore. Contribute to internal project/programme team meetings and help inform go/no-go decisions. Establish and support collaborations with internal and external partners to accelerate oncology research. Keep up to date with scientific literature and contribute to peer-reviewed publications and patents. Provide technical training and mentorship to support team members. Experience & Knowledge: Essential: Deep understanding of immunology and cancer cell biology. Significant prior pharmacology experience with therapeutic molecules. Extensive experience with a broad range of immunoassay techniques. Experience in generating in vitro models of cancer. Excellent written and oral communication skills. Desirable: High throughput screening. 3D in vitro modelling experience. Experience with omics technologies. Bioinformatic expertise. In vivo pharmacology experience. Education & Qualifications: PhD or equivalent in relevant disciplines. 5+ years’ experience of post-doctoral research. MSc or BSc with role-specific equivalent experience.
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Vacancy Name:
Senior Research Scientist II – Oncology Research, Functional Pharmacology Vacancy No:
VN454 Employment Type:
Full Time Location of Role:
Abingdon, UK About the Company:
Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases, and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. Key Responsibilities: Lead projects and collaborate with colleagues to build pharmacology data on new drug formats (e.g., TCRm, multi-specifics) and effectors (including immune checkpoint- / cytokine-enhanced drugs). Establish in vitro assays for immunophenotyping drug MOA and response/resistance relationships. Establish drug libraries and screening workflows for investigating drug combinations and their effects on target/disease biology. Identify and test novel strategies to block/reprogramme immune or stromal cell subsets that generate suppressive TMEs. Generate patient stratified in vitro models of disease that accurately model drug target biology. Other Responsibilities: Collaborate with colleagues to build a deep knowledge around drug targets and cancer indications of strategic interest to Immunocore. Contribute to internal project/programme team meetings and help inform go/no-go decisions. Establish and support collaborations with internal and external partners to accelerate oncology research. Keep up to date with scientific literature and contribute to peer-reviewed publications and patents. Provide technical training and mentorship to support team members. Experience & Knowledge: Essential: Deep understanding of immunology and cancer cell biology. Significant prior pharmacology experience with therapeutic molecules. Extensive experience with a broad range of immunoassay techniques. Experience in generating in vitro models of cancer. Excellent written and oral communication skills. Desirable: High throughput screening. 3D in vitro modelling experience. Experience with omics technologies. Bioinformatic expertise. In vivo pharmacology experience. Education & Qualifications: PhD or equivalent in relevant disciplines. 5+ years’ experience of post-doctoral research. MSc or BSc with role-specific equivalent experience.
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