Senior Research Nurse
Human Challenge Facility
Salary: NHS Agenda for Change, Band 7: £47,810 - £54,710 (subject to change from April 2026)
Fixed-term appointment until 6th July 2027 (possibility of extension)
Based in Liverpool
The Liverpool School of Tropical Medicine (LSTM) is a world leader in infectious disease research, and our Human Challenge Facility (HCF) plays a key role in accelerating the development of vaccines, diagnostics, and therapeutics that improve global health. We are an expert team in Controlled Human Infection Models, working to advance clinical interventions for disadvantaged populations worldwide.
We are seeking a Senior Research Nurse to take on a leadership role within the HCF, overseeing the clinical operations and staff. The postholder will be instrumental in operationalising the facility for its first inpatient study, ensuring quality, integrity, and excellence in clinical trial delivery.
Key Responsibilities:
Strategic and Leadership Duties
Lead the day-to-day management of clinical activities within the HCF.Oversee the clinical team and visiting staff, ensuring smooth operations.Support the Clinical Operations Manager and deputise when required.Implement processes to ensure high-quality research delivery aligned with Good Clinical Practice (GCP) and UK Policy Framework for Health and Social Care Research.Act as a key point of contact between the research team, NHS, external agencies, and LSTM departments.Clinical Responsibilities
Conduct research visits, clinical assessments, and procedures such as venepuncture, vital signs monitoring, and respiratory sampling.Assist in research bronchoscopy procedures, ensuring safe patient care.Administer treatments and investigational drugs in accordance with study protocols.Ensure study-specific investigations are completed per protocol requirements.Manage caseloads of study participants and ensure safety monitoring.Research & Compliance
Manage a portfolio of clinical studies, ensuring adherence to protocols and regulatory frameworks.Assist in obtaining informed consent, assessing participant eligibility, and ensuring study compliance.Record and report adverse events, study deviations, and safety concerns appropriately.Identify and implement strategies for participant recruitment and retention.Ensure data collection is accurate, complete, and stored in compliance with regulatory standards.Training & Development
Develop and deliver training for staff across clinical, laboratory, and trial management teams.Support junior team members and ensure their professional development.Maintain up-to-date clinical and research competencies, including mandatory training.Engage in research-specific training and amendments to study protocols.Administrative & Operational Duties
Develop and review study-specific documents and Standard Operating Procedures (SOPs).Maintain databases and accurate records of participant activity and financial tracking.Oversee resource management, including medical supplies and consumables.Coordinate recruitment events and public engagement initiatives to promote research participationThis role will require flexible working arrangements and may include out-of-hours working and night shifts.
The Ideal Candidate Will Possess:
Qualifications & Training:
Registered Nurse (Adult) with NMC registration (Essential)Degree in a healthcare-related field Good Clinical Practice (GCP) certificationBLS/ILS certification Skills & Experience:
Experience leading and managing a clinical team Significant experience in clinical research Experience coordinating clinical trials, including regulatory compliance Proficiency in venepuncture, IV cannulation, and clinical investigations Strong project management and organisational skills Experience in staff training and mentorship Competency with MS Office and electronic data management toolsWillingness to work flexible hours, including weekends and night shifts, as required In Return, We Offer:
30 days annual leave, plus bank holidays and additional Christmas closure daysGenerous occupational pension schemesGovernment-backed “Cycle to Work” schemeDiscounted staff membership at the University of Liverpool Sports CentreA supportive and inclusive working environmentRetain NHS Pension membership
